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Within the interim analysis, Xofigo significantly improved overall survival (OS) [HR=0.695 (95% CI 0.552 0.875), p=0.00185]; median OS was 14.0 months with Xofigo plus best standard of care (95% CI 12.1, 15.8) vs. 11.2 months with placebo plus best standard of care (95% CI 9.0, 13.2).1 Additionally, with the interim analysis there seemed to be a delay at some point to first symptomatic skeletal event (SSE) for patients given Xofigo vs. Placebo.
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